Carryduff firm Spanwall's role is to manufacture the rainscreen system for the structure. It works for the German contractor Metallbau Frueh with Belfast practice Todd Architects for Harcourt Construction Northern Ireland Limited.
The project is due to be completed in 2012 in time for the centenary of the Titanic's maiden voyage.
Spanwall's chief executive Tony Reid said the company's "highly skilled" workforce will play a vital role in the landmark project, which is set to become the cultural centrepoint of Belfast city's new Titanic Quarter development.
The firm's design director Alan Grimason, who has been very involved in the design, said that Spanwall is proud to be involved in the contract.
"It it is perhaps one of the most prestigious structures that will have been built in Northern Ireland in the last hundred years," he said. "We look forward to working with Metallbau Frueh, Harcourt and Todd Architects on this landmark project."