Budget airline easyJet is to begin a new Manchester-Moscow service next year.
The carrier will start a four flights-a-week service to the Russian city in March.
EasyJet also said it was basing an eighth additional aircraft at Manchester in a move which will create 80 jobs.
The Manchester-Moscow service announcement follows news last month that easyJet had won rights to operate Gatwick-Moscow flights.
The no-frills airline expects to carry more than 60,000 passengers in the first 12 months of its Manchester-Moscow services. Customers will travel on 180-seater Airbus A320 aircraft.
EasyJet CEO Caroline McCall said: "Russia is a country rich in culture and history - so a direct link from the north of England is long overdue."