The BBC has ordered a fundamental review of taste and decency standards across the network in an attempt to end the row about lewd prank phone calls that has engulfed the corporation.
The controller of Radio 2, Lesley Douglas, one of the most influential figures in the radio and music industries, was forced to resign, while Jonathan Ross, the highest-paid man in British broadcasting, has been suspended for 12 weeks without pay.
His Radio 2 presenting colleague Russell Brand resigned on Wednesday.
The BBC Trust ordered an on-air apology to licence fee-payers for “serious and deliberate breaches” of editorial guidelines, and asked the director general, Mark Thompson, to write a personal apology for the scandal.
He declined to comment on the future of more junior staff involved but promised to conduct a review of guidelines.
The announcements came after six-and-a-half hours of crisis talks between Mr Thompson and the BBC Trust, following the latest in a succession of scandals since the 2004 Hutton report, which forced the resignations of the then director general Greg Dyke, chairman Gavyn Davies and reporter Andrew Gilligan.
The BBC had initially tried to play down the latest furore, which was caused by four messages left by Jonathan Ross and Russell Brand on the answering machine of the 78-year-old former Fawlty Towers actor Andrew Sachs, discussing his granddaughter's sex life.
But by yesterday evening the BBC had received more than 35,000 complaints about the broadcast, and it had become clear that at least one senior resignation would be required to contain the scandal.
In a statement last night, Ms Douglas said: “The events of the last two weeks happened on my watch. I believe it is right that I take responsibility for what has happened.”
In her resignation letter to Mr Thompson, Ms Douglas acknowledged that the past week had been a “painful one for the BBC and particularly for BBC Radio 2”, writing: “Over the 23 years of my career at the BBC I have enjoyed a deep love and respect for both the audience and the BBC.
“It is with enormous regret that I have decided to resign as Controller of BBC Radio 2, BBC 6 Music and of Popular Music. This is my decision alone.”
Mr Thompson said he accepted the decision with “real sadness”. He added that Ross had been suspended for three months without pay.