Century 21 Gold agent Lisa Tiger says the six-bedroom home in Wyomissing, near Reading, Pennsylvania, is in contract and expected to close this month.
Taylor's parents had rented the home for many years before moving to Nashville when the singer was 14.
The classical revival home boasts a grand staircase and a sun-filled study where Swift played guitar, according to the 799,000 US dollars (£522,000) listing.
Taylor's 2012 album Red includes the song Begin Again. The 23-year-old Swift has sold more than 75 million albums.
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