Her representative, Melissa Kates, said the actress married tennis pro Ryan Sweeting in a New Year's Eve ceremony at a ranch in Santa Susana, California.
Afterwards, the 28-year-old posted a few photos with her 26-year-old husband on her Instagram account.
She wore a pink Vera Wang wedding gown and captioned one picture as "Greatest night of my entire life".
The couple dated for three months before getting engaged in September.
Kaley had previously dated her Big Bang Theory co-star Johnny Galecki.
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Working in isolation doesn't suit you. You're a social creature who gets your best ideas when collaborating with others. Unfortunately, that's not possible right now. Resign yourself to this difficult situation. If you do a good job, you'll pave the way for bigger and better assignments. Part of the problem is you lack experience. The only way to get the training you need is to do some volunteer work. Making a temporary sacrifice will eventually pay off. Be patient.More