Brian Dowling is the bookies' favourite to take the Ultimate Big Brother crown as Channel 4 waves goodbye to the long-running reality show.
The former air steward, who entered the house in 2001 as an unknown, is expected to beat off competition from other former contestants to be named the viewers' favourite.
The final will also mark the end of Big Brother's 10 years with Channel 4 which announced last summer it would not be renewing its deal with programme-maker Endemol.
The reality show may not end, however, as media tycoon Richard Desmond said he was thinking of reviving it when he took over the Five TV network in July.
Bookies Paddy Power and William Hill both made Brian the favourite to win, with odds of 2/9.
Chantelle, who won Celebrity Big Brother in 2006 despite being the only housemate who was not actually famous, is second favourite to win. The model, who had to pretend to be a singer with fictional pop band Kandy Floss to fool her fellow contestants, married Ordinary Boys singer Preston after the pair met on the show.
They split within 10 months and later divorced but viewers hoped for a reconciliation after both returned to the house this summer.
Paddy Power offered odds of 7/2 on Chantelle winning the final while Preston is trailing on 33/1.
Third favourite is tantrum queen Nikki, who first entered the house in 2006 dressed as a Playboy bunny. William Hill has Nikki on 10/1 while Paddy Power rates her chances as slightly better on 8/1.
Also in the running for the crown are "Nasty" Nick, Ulrika and Victor. Vanessa, Coolio, John McCririck, Nadia, Makosi, Josie and Michelle have already left the house.