Grapefruit poses a potentially lethal health risk to increasing numbers of patients taking prescription drugs, experts have warned.
The fruit contains chemicals that can interact with certain drugs to then make them more potent.
Adverse effects can include acute kidney failure, respiratory failure, internal bleeding and sudden death.
While it is well-known that some patients should avoid grapefruit, or grapefruit juice, the list of drugs involved has risen sharply in recent years, said scientists writing in the Canadian Medical Association Journal.
The list of danger medicines includes treatments for anxiety, depression, allergy, HIV infection, seizures, heart rhythm abnormalities and high cholesterol.