The Cork air crash disaster starkly shows how fragile life can be, Northern Ireland's First Minister has said.
Peter Robinson said he was shocked by news of the tragedy, which drew condolences from across Ireland, north and south, and at Westminster.
He said his thoughts are with the families and friends of those involved, adding: "This is I think testimony to the unquestionable uncertainty of life.
"Families that start out either to do a day's business or to enjoy some pleasure have been thrust into circumstances that they could not have imagined."
He added: "This is a terrible tragedy and my thoughts are with the families of the bereaved. My thoughts are also with the injured and I hope that they will make a full and speedy recovery."
The Deputy First Minister Martin McGuinness said: "I am shocked at this news and want to convey my condolences to the families, friends and loved ones of those who have lost their lives in the plane crash. My thoughts are also with those who have been injured."
Both men visited Belfast City Airport where the flight took off. They said the Stormont administration is offering all the help that it can and that Transport Minister Conor Murphy is in contact with his counterpart in the Republic.
Northern Ireland Secretary of State Owen Paterson said: "This is a terrible tragedy. I offer my profound condolences and sympathy to the families and friends of those killed and injured. I have spoken to our Ambassador in Dublin who is on his way to Cork and who will be working closely with the Irish authorities."
East Belfast MP Naomi Long, whose constituency includes the City Airport, said: "It is a very dark day for both Belfast and Cork.
"My thoughts and prayers are with the families of those who have been killed or injured, and I know that the whole community will be thinking of them at this difficult time, and would join with me in wishing those who have survived a full recovery."