A US pharmaceutical company has announced the creation of 500 jobs in Dublin and Galway.
Mylan will invest 76 million euro into its Irish workforce every year over the next five years and hopes to fill the positions by 2016.
The majority of the jobs will be based in the firm's existing Dublin branch, with 220 in Galway.
Taoiseach Enda Kenny made the announcement at the Dublin facility.
The announcement, "in addition to the company's proven 25-year track record as a top employer and reliable exporter in Ireland, demonstrates Mylan's commitment to its Irish operations and recognition for the capabilities of its talented workforce," he said.
IDA, the enterprise organisation responsible for attracting foreign investment into Ireland, described the expansion as a positive development for the life sciences sector.
Mylan employs 700 people at its Irish facilities. The company delivers pharmaceutical products to customers in an estimated 150 countries around the world.
The jobs boost will see increased research and development, and manufacturing capabilities within the firm's respiratory, injectables and oral solids franchises.
Jobs Minister Richard Bruton, who also attended the launch, said the news is evidence that the Government is on track with its Action Plan for Jobs, which aims to deliver 100,000 new jobs by 2016.
"The life sciences industry is a key part of this Government's strategy for jobs and growth," Mr Bruton said. "Employing approximately 50,000 people here directly, the sector is a major strength in Ireland, but we must build on this."