Taoiseach Enda Kenny will travel to Paris to hold talks with French president Francois Hollande.
Ireland's debt woes are sure to feature high on the agenda during Mr Kenny's first bilateral meeting with Mr Hollande in France.
Dublin's bid to ease the burden of its multibillion-euro bailout repayment programme was thrown into uncertainty on Friday after German chancellor Angela Merkel indicated that debts racked up in the past would not be covered by a new emergency fund to recapitalise banks.
While the German and Irish administrations subsequently insisted they were both still committed to working together to improve the sustainability of Ireland's debt, doubt remains over an agreement struck by European leaders in June that potentially would have seen Irish repayment terms improved.
With tensions also marking recent relations with Mr Hollande and Mrs Merkel, Mr Kenny may find a more sympathetic ear in Paris.
Irish preparations for the EU presidency and relations between the two states are also set to feature in the talks.
The meeting forms part of the Taoiseach's ongoing engagement with other EU leaders and European heads of government.
Before his meeting with the French president, the Taoiseach will attend a business event hosted by the Irish Embassy for clients of Enterprise Ireland, IDA (Industrial Development Agency) and Bord Bia.
The Taoiseach will also meet the France-based members of the Global Irish Network and 'Network Irlande', the Franco-Irish business network.
Later, the Taoiseach will launch Bord Bia's 'Origin Green' initiative at the SIAL food fair. The initiative aims to promote Ireland's international reputation as a source of natural, high quality, sustainable food, drink and ingredients.