About 200 plants and cultivation equipment were seized when gardai were called to a property in Chapelwood, Kilmuckridge, on Sunday.
Gardai said the plants have an estimated street value of 240,000 euro, subject to analysis.
A man in his early 60s was arrested at the scene and taken to Enniscorthy Garda Station, where he is being detained under Section 2 of the Criminal Justice (Drug Trafficking) Act 1996.
He can be detained for up to seven days.
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