A total of 100 hi-tech jobs have been created at a multi-national medical devices company.
Nypro Healthcare is to expand its centre of excellence in the seaside town of Bray, Co Wicklow.
The new jobs, announced by Taoiseach Enda Kenny, bring the firm's total Irish workforce to 460.
"Ireland's reputation as a leading location for business and investment in the life sciences sector is further boosted by this announcement of 100 new highly-skilled jobs at Nypro's Bray facility," Mr Kenny said.
He said maintaining Ireland as an attractive location for investment was a priority for the Government.
The jobs announcement was supported by IDA Ireland, which is responsible for attracting direct foreign investment to the country.
Jobs Minister Richard Bruton also hailed the new positions, saying the announcement was further evidence of the strong potential for the healthcare sector.
"Healthcare and life sciences is a key sector targeted by the Government for employment growth as part of the Action Plan for Jobs," Mr Bruton said.
He added that the expansion was also great news for Bray and that he was determined to build on it to create further growth and employment.
Nypro, a US-based firm which set up shop in Ireland in 1980, changed direction in 2008 - moving from a focus on the electronic industry to drug delivery and diagnostics. It has created 160 jobs in the last two years.