Fifty jobs are to be created at a pharmaceutical company in Dublin.
Alexion, which makes drugs for people with rare disorders, said it will take on the new staff by the end of the year.
The roles are in supply chain, quality assurance, quality control and logistics.
The opening of Alexion's Irish office and laboratory is being supported by the taxpayer through the State investment agency IDA.
Jobs Minister Richard Bruton said the announcement was a significant boost for the pharmaceutical industry here.
Stephen Squinto, executive vice president at Alexion, said Ireland's "unparalleled commitment" to education and training for pharmaceutical manufacturing was behind the move.
"For these reasons, as we continue to expand our global supply chain and quality team, we are very pleased to come to Ireland for its highly skilled and educated workforce," he said.