More than 150 jobs are to be created in two separate investments.
Cloud-based computer firm FeedHenry is to create 100 jobs over the next two years after securing 7 million euro funding for the roll-out of its mobile application business.
In the second announcement, online car parts and accessories retailer MicksGarage.com will take on 65 staff over the next two years on the back of a 2.3 million euro investment.
Cathal McGloin, chief executive of FeedHenry, said recruitment is to begin immediately for software engineers, project managers and business analysts.
"Increasingly, enterprises are viewing mobile apps as transformative to their business operation," he said. "As organisations evolve towards more complex apps with connections to multiple backend systems, the need for a cloud-based mobile application platform is compelling. This new investment will give us the means to continue to innovate and expand the capabilities of our platform to better serve our growing customer base."
FeedHenry was originally a research and development project set up at Waterford IT.
The MicksGarage announcement was made as Taoiseach Enda Kenny opened the company's new 32,000 square feet warehouse and office facility in Park West, Dublin.
Founded in 2004, it has grown to become one of Europe's largest car parts and accessories online retailers, delivering products across Ireland, the UK and mainland Europe. The business, which currently employs 34 staff, was set up by brothers Ciaran and Michael Crean, from Ballina, Co Mayo.