Almost 900 more people are admitted to hospital every day for drinking compared to five years ago, figures show.
A round-up of existing data shows there were 1.1 million admissions in England relating to alcohol in 2009/10 - 879 more per day than five years previously.
There is also wide variation across the country in rates of hospitalisation, with 3,114 admissions for alcohol per 100,000 people in Liverpool, dropping to 850 per 100,000 on the Isle of Wight.
Overall, in the five years to 2009/10, there was a 25% rise in the number of people admitted for reasons that were due to drinking.
Other figures show 7.6% of drinkers are now considered high risk, meaning they are at serious risk of jeopardising their health.
That is set against a backdrop of increasing numbers of people suffering and dying from chronic liver disease.
The report, from the North West Public Health Observatory at Liverpool John Moores University, also contains new estimates on the number of people in England who do not drink at all.
There are thought to be six million people over 16 who do not drink, with people from certain ethnic or religious backgrounds far more likely to abstain.
Other detail, drawn from official crime statistics, shows there were 392,787 crimes attributable to alcohol in 2010/11 - 7.6 crimes per 1,000 people.
The highest rates of crime linked to drinking by region occurred in London (11.7 crimes per 1,000 residents) while the north east had the lowest rate (5.7 per 1,000 residents).