The current editor of The Sun Dominic Mohan, who has steered the tabloid through one of its most turbulent times, is leaving the paper.
Mohan, who has edited the red top since 2009, is to take up a senior role advising the chief executive of the new News Corp - formed after Rupert Murdoch decided to split the firm's newspaper and entertainment operations.
He is being replaced by former Scottish Sun editor David Dinsmore, who will take the helm on Monday.
Mohan, who has been with the Sun for 17 years, said: "It has been a real privilege to edit The Sun, an intrinsic part of modern Britain, loved by its readers and unmatched by its rivals.
"I am proud of the way we have informed and amused our readers in recent years and also campaigned on their behalf in difficult economic times. I would like to thank my peerless staff for the creativity and spark they have brought to the paper day after day.
"I am confident The Sun will go from strength to strength, and now look forward to a new challenge of helping a brand new company find its feet and build a strong future for its journalism across the globe."
A statement from News International said Mohan will advise the chief executive of the new News Corp, which will officially be incorporated next Friday, and will be tasked with exploring opportunities for it across Europe.
He will be replaced on Monday by 44-year-old Glaswegian Dinsmore, who worked his first shift on the paper at the age of 22.
Dinsmore became editor of the Scottish edition in 2006 and was promoted to general manager of the company's operations in Scotland in 2010. After a brief stint as the managing editor in London, he joined the executive of News International last October as director of operations.
"There is no better job in journalism than editing Britain's most popular paper," he said.