Women in Antrim and Newtownabbey have lowest healthy life expectancy in the UK
Women in Antrim and Newtownabbey areas of Northern Ireland can expect just 51.4 years in good health - the lowest in the UK.
The New Office for National Statistics (ONS) figures show a two-decade gap between "healthy life expediencies".
Male residents of Rutland in the East Midlands can expect to live 71.8 years of their lives in good health.
But men who live in Tower Hamlets in London have a healthy life expectancy of just 54 years, the ONS said.
Women in the Orkney Islands have a healthy life expectancy of 74.6 years.
Commenting on the figures, Janet Morrison, chief executive of the charity Independent Age, said: "Health inequalities are deeply embedded in the UK.
"It should not be acceptable that people in an area like Rutland can expect nearly 72 years of good health while those in Tower Hamlets can expect only 54 years.
"At a time when funding for the NHS and social care is extremely stretched, improving healthy life expectancy in all areas of the UK is essential if we want to reduce the costs of an ageing population.
"If we have a public health and care system that helps people to live longer lives in better health, it is better for them, but also better for everyone."
The new ONS figures show that newborn baby boys can expect to live for 79.2 years and a newborn baby girl 82.9 years if mortality rates remain the same as they were in the UK in 2013-2015.
The figures also highlight regional differences between life expediencies , with men in Kensington and Chelsea expected to live 83.4 years while those in Glasgow are expected to live 73.4 years.
Women in Hart in the south east of England have a life expectancy of 86.7 years while those in West Dunbartonshire can expect to live to 78.7.
The ONS said that women continue to have higher life expectancy estimates than men, but males live a higher proportion of their lives in good health and disability-free.
Sarah Caul, senior health researcher at the ONS, said: "Improvements to healthcare and living healthier lives means that as a nation we are living longer and newborn boys and girls can expect to live for 79 and 83 years respectively.
"However, while we are living longer we are spending a smaller proportion of our overall lives in good health which puts a greater challenge on health services."
A Department of Health spokesman said: "We want to see people living a healthy, high quality life for as long as possible.
"It is unacceptable to see so much inequality across the country but we know local areas are taking positive steps to tackle lifestyle factors like high smoking or obesity rates which contribute to poor health."