Experts eye fertility breakthrough
Scientists hope to try to fertilise the first human egg cells grown in the laboratory from stem cells later this year.
The move would mean a potentially unlimited supply of human eggs could be produced, a "breakthrough" in fertility treatment.
It could also lead to further developments in relation to alleviating conditions associated with the menopause.
University of Edinburgh researchers are working with a team from Harvard Medical School in Boston to be the first to produce mature human eggs from stem cells isolated from human ovarian tissue.
They aim to request a licence from the Human Fertilisation and Embryology Authority (HFEA), the UK fertility watchdog, to try to fertilise the lab-grown egg cells with human sperm to prove they are viable.
If any embryos were produced they would then undergo "robust" scientific and genetic testing to determine that they are normal.
Current methods mean only a small number of human egg cells are generated directly from the ovaries of women who have had hormonal stimulation.
Dr Evelyn Telfer, a reproductive biologist at the University of Edinburgh, said: "With every experiment you don't know the outcome.
"Even if we get an egg fertilised we don't know it will be normal. Any positive results could mean a breakthrough for fertility treatment. The exciting thing is these cells have been isolated and we have a lot more study to do."
The team hope to do the tests at the IVF unit at Edinburgh Royal Infirmary this year once the licence is in place.