Long-time pianist George Horner will play with the renowned cellist Yo-Yo Ma at Boston's Symphony Hall.
The concert is in aid of the Terezin Music Foundation, an organisation dedicated to preserving the work of artists and musicians killed by the Germans.
Mr Horner, now a retired doctor living near Philadelphia, said it was a noble endeavour to carry on the musical legacy of Holocaust victims.
Event organiser Mark Ludwig called the concert "an extraordinary link to the past".
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