A coroner who conducted the autopsy on Michael Jackson says there is no evidence supporting the theory by lawyers for Dr Conrad Murray that the star gave himself a fatal dose of the anaesthetic propofol.
Dr Christopher Rogers also told a jury in Los Angeles that the singer was healthier than most people his age and his heart did not show the usual signs of fatty build-up generally seen in men the same age.
Dr Rogers explained how coroner's officials determined the 50-year-old singer died in June 2009 from acute propofol intoxication.
The determination led to prosecutors charging Murray with involuntary manslaughter.
The cardiologist has pleaded not guilty.
Earlier, the trial heard Murray describe how he told Jackson's family about the superstar's death.
Prosecutors continued playing his taped interview with police on the trial's 10th day.
Murray calmly told detectives on June 27, 2009, about how he told Jackson's mother and held her hand while she cried.
He also described Jackson's daughter's fears about being left an orphan.