Pope Benedict XVI has urged Christians to remain strong in the face of intolerance and violence in a New Year's appeal that came several hours after a bomb blast outside an Egyptian church that killed at least 21 people as worshippers left Mass.
The Pope condemned a widening campaign against Christians in the Middle East in his homily at St Peter's Basilica, echoing comments last month in which he called a lack of religious freedom a threat to world security.
"In the face of the threatening tensions of the moment, especially in the face of discrimination, of abuse of power and religious intolerance that today particularly strikes Christians, I again direct a pressing invitation not to yield to discouragement and resignation," he said.
Benedict has repeatedly denounced a campaign against Christians in Iraq blamed on al Qaida militants, including an October attack on a Baghdad Roman Catholic church that claimed 68 lives, two of them priests.
The Vatican is worried that a steady exodus of minority Christians from Iraq will permanently reduce their numbers and discourage the wider community of Christians in the Middle East.
Benedict cited what he called two negative extremes at work in the world - secularism, "pushing religion to the margins to confine it to the private sphere", and "fundamentalism, which instead would like to impose (religion) with force on all".
The Vatican celebrates New Year as World Peace Day, and Benedict urged world leaders to make a "concrete and constant commitment" to help bring peace.
On Saturday, a bomb exploded in front of a Coptic Christian church in the Egyptian city of Alexandria, killing at least 21 people in an attack that raised suspicions of an al Qaida role.
Benedict recalled his speech last month in which "I stressed that religious freedom is the essential element of a state of law - you cannot deny it without, at the same time, undermining all rights and fundamental freedoms".