Investigators say they are looking into whether the man had suffered a medical emergency before the accident. The driver was being treated and has not been identified.
About 50 to 60 people suffered injuries ranging from critical to superficial, but no fatalities were reported. Three of the worst injured were flown by helicopter to area hospitals.
It happened during the Hikers Parade at the Trail Days festival, an annual celebration of the Appalachian Trail in Damascus, near the Tennessee state line.
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