Clashes between police and supporters of Egypt's ousted president have left at least seven people dead, officials said today.
At least 261 people were injured in the violence in four different locations in the capital, Cairo, the health ministry said.
Thousands of supporters of Mohammed Morsi, who was overthrown by the military, were protesting to press their demands that he be reinstated as president. Egypt's military deposed Mr Morsi on July 3 after days of mass street protests calling for him to step down. The ousted president's supporters say he was removed by a military coup that overturned democratic rule.
There was no official word on how the seven died, but security officials said four were killed in clashes between Morsi supporters staging a sit-in near the main Cairo university campus and residents of the area.
Egypt's state news agency said 17 policemen were injured in the violence, and 401 people have been arrested in relation to the clashes.
The protest turned violent as pro-Morsi protesters burned tyres, threw rocks and firebombs and blocked traffic flow on a main road running through the heart of the capital.
The police fired volleys of tear gas, and the Muslim Brotherhood, the Islamist group from which Mr Morsi hails, said officers also used birdshot and live ammunition.
Thousands of Morsi supporters have been staging sit-ins in two locations in Cairo, one outside the main campus of Cairo University and another outside a mosque in a neighbourhood in eastern Cairo that is a Brotherhood stronghold.
Mr Morsi and the Brotherhood insist that loyalists of the deposed autocrat Hosni Mubarak, who was toppled by Egypt's 2011 uprising, worked incessantly to undermine Mr Morsi's rule and that a wave of protests and strikes prevented him from introducing reform.
The bloodshed, which comes a week after army troops and police killed more than 50 Morsi supporters, made clear the determination of the pro-Morsi camp to resist the new political order and to maintain pressure on the military and the interim administration to offer concessions.