Phil Jagielka admitted England were "absolutely devastated" as their late 2-1 loss to Uruguay left them on the brink of World Cup elimination.
Luis Suarez scored twice, the winner coming in the 85th minute, after Wayne Rooney's equaliser had given England hope of getting something out of the game.
The loss was the second in two matches for Roy Hodgson's men and left them needing to beat Costa Rica in the final match and other results to go their way to qualify.
"As you can tell by my voice everyone's absolutely devastated," Jagielka said on ITV.
Suarez headed his first goal home from Edinson Cavani's cross and for his second ran on to a misplaced Steven Gerrard header and blasted past Joe Hart.
"Gutting, played so well again in spells, unfortunately a little bit of luck went against us, Steven flicking the ball on and Suarez gets the wrong side," Jagielka said. "Pretty disappointed, boot down the pitch, flick on and the goal."
Asked if he thought Suarez was the difference between the sides, the Everton man added: "Yes and no, I think the cross for the first goal was pretty decent as well. Similar to the Italy game, (we) played pretty well, but not good enough."
Hodgson could not hide his desperation at the manner of his team's defeat.
"We are more then disappointed, we're devastated," he said. "We believed we could do enough to get a result in this game. Having worked so hard to get back to 1-1 I believed we would go on to win the game or at least draw, so to concede the second goal is an unbelievable blow. I don't really know what to say at this time.
"It was a goal we don't expect to concede. Long goal kicks with the type of players we have in the team, we deal with them.
"I thought we would go on possibly to win the game and certainly I didn't think we would lose the game at that point.
"We had been in control for such a long time. After the first five minutes (of the second half) we got back on track. We've been near their goal so many times, but it doesn't matter how many times you get near the other team's goal, it matters how many times you put it in the back of the net and we haven't done that enough."
On Suarez, he said: "He scored the two goals. The first goal in particular was exceptionally good, Cavani's chip and his pulling away to the back post and the cleverness of his header I thought was really top, top play. The second one I thought he was a bit fortunate, but when he got himself through he made no mistake."
Suarez said afterwards: "I dreamt this. I'm enjoying this moment, because of all I suffered, the criticism I received. So, there you go."
Suarez in focus
Luis Suarez was the hero for Uruguay as they beat England 2-1 in World Cup Group D, the Liverpool striker netting both his side's goals including an 85th-minute winner after Wayne Rooney had equalised.
We take a look at how Suarez, back in the Uruguay starting line-up after a knee operation, fared in the victory.
Any England hopes Suarez had been rushed back from his knee injury too early were dashed early on. Sensibly opting not to waste energy chasing lost causes, he focused on when and where he could hurt England.
He showed much better movement than the ageing Diego Forlan, whom he replaced, had against Costa Rica, giving the England back-line plenty to think about. There was no let-up, either, grabbing the winner five minutes from time before being replaced three minutes later.
He was at the centre of all of his side's attacking endeavours, showing the subtlety and guile his team-mates had lacked in their first game. He linked up very well with Edinson Cavani, who also turned in a much improved display.
England's defence struggled to cope with the combination between the pair. Indeed, Suarez's return seemed to have a positive affect across the team, who all looked sharper, closed down quicker and were snappier in possession.
He almost caught Joe Hart out twice low at the near post direct from a clever corners. And he made Roy Hodgson's side pay with his first chance. He peeled off Phil Jagielka to meet Cavani's perfectly-flighted cross and sent his header back across goal and inside Hart's right-hand post.
He dragged a presentable second-half chance wide, but was deadly accurate late on as he pounced on Steven Gerrard's misplaced header and lashed home the winner.
Uruguay may not be a one-man team, but are pretty close to one on this showing.
They were a totally different side to the which were so poor against Costa Rica and that was down in large part to Suarez.
Two clinical finishes from the Liverpool man were the difference between the sides.