Mayo opened their NFL Division One campaign with a 0-15 to 1-6 win over 14-man Kerry at Castlebar.
The Kingdom failed to score in the second half, having had midfielder Anthony Maher sent off for a second booking in the 49th minute.
Kerry's only point in the first 15 minutes came from Michael O'Donoghue, as Mayo forged ahead with four Jason Doherty points.
But the Kingdom suddenly began to carry a threat at the end of the opening quarter.
Darran O'Sullivan set up James O'Donoghue, but his shot was superbly saved by David Clarke.
In the 17th minute, O'Donoghue finally did find the net, but the home side responded with points from Doherty and Kevin McLoughlin.
They were level on 0-9 to 1-6 at the interval, but Mayo full back Ger Cafferkey repeatedly frustrated Kerry's attacking efforts, and they were unable to break down a tenacious Mayo attack.
And the home side saw off their opponents with a late flourish which saw Enda Varley come off the bench to shoot a couple of points.