Antrim lost to old foes Sligo at a wet and windy Markieivicz Park.
Frank Dawson's side started brightly with the Murray brothers Ryan and Conor both scoring in the early stages, but Sligo took complete control thereafter and went on to take victory.
The Antrim defence couldn't cope with the movement of the Sligo forward line with Mark Breheny, Adrian Marren, Brian Curran, Neil Ewing and James Clarke all scoring in a dominant first half.
The decisive moment of the half arrived on 25 minutes when Sligo's Pat Hughes ran through the Antrim defence, dribbling soccer-style before lashing the ball to the net.
Antrim got off to a blistering start in the second half scoring six without reply, with half time substitute Paddy Cunningham showing well.
But their momentum was checked after 50 minutes when Kevin Niblock was sent off for a second booking.
Still, the Antrim side worked hard and reduced the deficit to two points as the final whistle approached.
However, Michael Magill was given a straight red card soon after being introduced for an off-the-ball tussle with Sligo's Ross Donovan and with that Antrim's hopes of an unlikely comeback and two crucial National League points ended.
Sligo were good value for their victory.
Sligo: P Greene, N Ewing 0-1, J Martyn, C Harrison, M Quinn, R Donovan, B Curran 0-1, S Gilmartin, A McIntyre, S McManus, J Clarke 0-1, P Hughes 1-0, M Breheny 0-4, A Marren 0-4, N Murphy 0-1. Subs: F Quinn for J Clarke (52), B Egan for N Murphy (60)
Antrim: J Finucane, K O'Boyle, P Doherty, N Delargy, T Scullion, J Crozier 0-1, J Laverty, M McCann 0-1, J Carron, C Murray 0-2, K Niblock 0-1, B Herron, R Murray 0-2, M Herron, M Pollock 0-2. Subs: S Finch for J Laverty (30 mins), P Cunningham 0-3 for Carron (35), C Kelly for M Herron (52), M Magill for R Murray (60), T McCann for C Murray (65)
Referee: L Devenny (Mayo)