Irishman Shane Lowry must look into other ways of qualifying for next April's US Masters after illness led to him withdrawing from the last event of the European Tour season.
A good week at the £6million DP World Tour Championship in Dubai could have lifted the 25-year-old into the world top 50 for the first time - and at the end of next month they all earn invitations to Augusta.
"Obviously I'm gutted," said Lowry, who was put on a drip in hospital on Wednesday after going down with a virus.
"It's such a big week and a great event, but given the way I feel right now there's just no way I could have played.
"I honestly couldn't even stand up on the tee, never mind play 18 holes.
"I became very sick and dehydrated. The drip helped, but when I came off it and left the hospital I became sick again and haven't been able to keep rehydrating to keep the recovery going overnight.
"It's just so disappointing to miss out on the tournament because I've been playing great for the last couple of months."
He won the Portugal Masters and then came fifth at the BMW Masters in China.
"I was looking to end the season on a real high, but such is life."