Belfast will host the 2012 event on Bank Holiday Monday 7th May.
More than 20,000 runners are expected to hit the streets of North, South, East and West of the City.
The event has grown with the inclusion of new sponsors which now include Deep RiverRock, Belfast City Council, Sport Northern Ireland, Daily Mirror, Donnelly Group, Athletics Northern Ireland, Premier Inn, Translink, Up and Running, Saucony and U105.
The official nominated charity for the 2012 event is the Northern Ireland Children's Hospice.
The route will remain the same as the 2011 event; starting at the City Hall and finishing at Ormeau Park.