Carl Frampton will now defend his IBF Inter-continental super-bantamweight title against Everth Briceno on July 20 at Wembley Arena.
Original opponent Fabian Orozco was knocked out in two rounds at the end of last month and therefore ruled out of the London bill so now he faces 35-year-old Briceno from Chinandega, Nicaragua.
Briceno boxed for the WBO World super-flyweight title three years ago, losing on points and holds a record of 35 wins, eight defeats and two draws.
"Everth Briceno is a great fighter. The guy has fought for the World title on two separate occasions. He also boxed Leo Santa Cruz who is a future rival of mine, so I aim to do a better job on Briceno than Cruz did.
"I am in the best shape of my life right now. I am improving in training every day, sparring great, and I'm looking forward to showcasing my skills at Wembley on the 20th."
Frampton, though, will be disappointed to learn that Kiko Martinez – who he stopped in emphatic fashion earlier this year – will challenge Jonathan Romero for the World title next month.
The Belfast man had been targeting a clash with Romero.
Meanwhile, former World heavyweight champion David Haye has confirmed that he will fight Tyson Fury on September 28 with Manchester the likely venue.
The pair have been trading insults for some time and now they can sort it out in the ring in what is one of the most highly anticipated fights of the year.