Richard Fahey could switch Wootton Bassett to the Abu Dhabi Irish 2000 Guineas on May 21 after ruling him out of this month's Newmarket version.
Fahey admitted earlier this week he had been desperate to get another key piece of work into his colt, who suffered a setback in his preparation earlier in the year.
Wootton Bassett won all five starts as a two-year-old, culminating in the Group One Prix Jean-Luc Lagardere at Longchamp last October.
The Malton trainer now hopes to run his star colt at either the Curragh or in the French 2000 Guineas the previous Sunday.
Fahey said: "We've just run out of time (for Newmarket). We've got to turn up 100% and we're not going to get there 100%.
"We've got another month or so for the French and the Irish Guineas so that gives us more time - it will be one or the other.
"It's a shame we're not going to Newmarket because I fancied taking Frankel on. Hopefully we'll meet him one day."
The John Hammond-trained Manhaj will also be scratched from the Newmarket race, and will instead have a later-season campaign.
The son of Medicean, who is owned by Sheikh Hamdan, won both of his starts as a juvenile, in a maiden at Maisons-Laffitte and a conditions event at Deauville last August.
"I'm taking him out of the Guineas - basically he's on the shelf at the moment and won't be out until the middle of the year," reported Hammond.