Aviva Premiership statistics
Friday, September 9
Sale (9) v Harlequins (5)
Sale boss Steve Diamond has made four changes from the side beaten narrowly by Newcastle last Friday. Wing Paolo Odogwu replaces Nev Edwards, while all of Diamond's other attention has been up-front, where hooker Neil Briggs starts instead of Rob Webber, lock Jonathan Mills is in for Andrei Ostrikov and David Seymour gains a back-row start, replacing Laurence Pearce.
Harlequins are unchanged following a tense victory over newly-promoted Bristol at Twickenham last Saturday. England full-back Mike Brown is continuing his recovery from illness, and Quins hope that he will available for next week's trip to Exeter. Two switches on the bench see call-ups for James Chisholm and Winston Stanley.
Last season: Sale 29 Harlequins 23, Harlequins 16 Sale 14 Last Six League Matches: Sale W W L L W L Harlequins L W L W L W
Top try scorers: Johnny Leota & Bryon McGuigan (Sale) 1; Joe Marchant & Marland Yarde (Harlequins) 1
Top points scorers: Johnny Leota (Sale) 5; Nick Evans (Harlequins) 11
Worcester (12) v Gloucester (7)
Worcester show three changes - all in the pack - following a 35-3 loss to Premiership champions Saracens last Saturday. Former Ireland lock Donncha O'Callaghan will partner Darren Barry in the second-row, with prop James Johnston and flanker Alafoti Faosiliva also starting. Back-row forward Phil Dowson will captain the team.
Gloucester rugby director David Humphreys has kept faith with the starting XV that lost at home to Leicester last Friday, despite building a 31-7 lead early in the second half. The only two alterations are among the substitutes, where prop Cameron Orr and centre Mark Atkinson come into the match-day 23.
Last season: Worcester 28 Gloucester 20, Gloucester 24 Worcester 22 Last Six League Matches: Worcester W L L L L L Gloucester L L W W L L
Top try scorers: Matt Scott (Gloucester) 2
Top points scorers: Ryan Lamb (Worcester) 3; Greig Laidlaw (Gloucester) 11