A hard-working performance from the in-form Highlanders saw them stamp their mark on the new Super 15 campaign with a stunning 35-28 victory over the Bulls in Pretoria.
Kade Poki ran in a brace of tries adding to scores from Adam Thomson and Josh Bekhuis, while fly-halves Robbie Robinson (six points) and Tony Brown (nine) also played their part to stun Loftus Versveld.
It meant three wins from three by the perennial Super Rugby strugglers and it also ended a run of 20 successive home wins for the 2009 and 2010 winners.
Meanwhile, Peter Grant kicked all 21 points to help the Stormers maintain their 100% start to the new season with a battling 21-15 victory over the Cheetahs in Cape Town.
The home number 10 landed seven out of eight kicks to see his side over the line.
Western Force are still looking for their first win of the campaign after the Sharks inflicted a 39-12 defeat in Perth.
The Force now remain the only Australian team yet to win this season, while the Sharks lead the South African conference after their bonus-point victory with three wins from three games.
Queensland Reds won for the first time in Canberra, beating the Brumbies 31-25, while the Chiefs overcame the Rebels 38-10.