Wales caretaker head coach Rob Howley is bracing his side for an Australia backlash this weekend as the Wallabies look to avenge their shock defeat to Scotland.
The Scots, who finished bottom of this season's Six Nations standings after losing all five of their matches, caused a major upset on Tuesday when they beat Australia 9-6 in Newcastle.
"Australia will be disappointed after their defeat to Scotland, but that will make them all the more dangerous for us," said Howley. "The Wallabies are still the second highest placed side in the world rankings and we are playing them in their own back yard."
Australia also have history on their side, having not lost on home soil to Wales since 1969, while the Welsh have not won away against a southern-hemisphere side in 25 years.
Howley added: "We all appreciate the enormity of the task ahead of us, the long term stats don't make happy reading for the Welsh against the Wallabies, but as recently as this season we have two losses racked up against Australian opposition and we are determined to stop that trend.
"We have created some winning momentum, we have a recent home win against the Barbarians to take into this game and have built a certain amount of confidence within the squad. We are well prepared and looking forward to the challenge this weekend."
Wales will head into the first of their three Tests against the Australians with 11 of the starting XV that clinched Grand Slam glory against France in March.
Despite seeing a fringe side beat the Barbarians 30-21 last week, Howley has picked a completely different team to that which played at the Millennium Stadium last weekend.
A total of 16 players were sent Down Under early for acclimatisation purposes, with all but Ashley Beck named to start the series opener.
Fit-again Sam Warburton will return to lead the side after an 11-week break since leaving the field at half-time in the 16-9 win over the French.