Alastair Kellock will captain a Scotland A side featuring nine Edinburgh players in the starting XV against the United States at Netherdale on Friday.
Glasgow Warriors lock Kellock, who captained Scotland to a historic series win in Argentina in June before undergoing knee surgery, leads the team, which features six members of the 33-man full Scotland squad named for the EMC Autumn Tests.
Scott Lawson, who came off the bench against New Zealand four days ago, will start in the front row alongside Geoff Cross, while Joe Ansbro, Jim Thompson, Ben Cairns and Alex Grove all get an outing behind the scrum.
Scotland A head coach Nick Scrivener said: "I'm really excited about the team we've put together. For what is a pretty young group, there's a lot of experience in there, and the challenge now is to make it count.
"It's fantastic to be able to call on a leader of the calibre of Al Kellock, and I know he'll set a great example for the younger guys to follow with the sense of purpose he'll bring to the game.
"The USA match is a great opportunity for any number of players to show they can come together as a group in a pretty short space of time and win a big game for their country.
"There's been a very clear link between the As and the senior side in the last couple of years, so there's no shortage of incentives for the boys to deliver."