Stade Francais fly-half Jules Plisson will make his France debut in Saturday's RBS 6 Nations clash against England.
The 22-year-old has won Les Bleus coach Philippe Saint-Andre's vote for the playmaker role in a team captained by Plisson's club colleague Pascal Pape.
Pape takes over leadership duties from flanker Thierry Dusautoir, who suffered a biceps injury in Heineken Cup action earlier this month and will miss the entire Six Nations tournament.
With Dusautoir sidelined, Racing Metro openside Bernard Le Roux is called up for the Stade de France clash. He will pack down alongside experienced back-row colleagues Yannick Nyanga and Louis Picamoles.
Plisson, meanwhile, will be partnered at half-back by Toulouse's Jean-Marc Doussain, with Mathieu Bastareaud and Wesley Fofana forging the midfield combination.
Heineken Cup quarter-finalists Toulouse provide the biggest representation from one club through a five-strong contingent of Doussain, Nyanga, Picamoles and wings Yoann Huget and Maxime Medard.