Dave Walder's late drop goal saw Wasps end Sale's unbeaten home record and claim their first away win of the Aviva Premiership season with a 25-24 victory in a scrappy encounter at Edgeley Park
The Londoners had trailed 24-19 heading into the final quarter but fly-half Walder, who ended with 20 points, struck his fifth penalty before slotting the crucial kick from dead in front of the posts with just two minutes remaining.
The win sees Wasps leapfrog Sale and climb to seventh in the table.
Walder's opposite number Charlie Hodgson marked his first start of the season with all his side's points in a flawless kicking display but it was not enough as Mike Brewer's side were denied at the death.
The scores had been level at 12-12 at half-time after a mistake-riddled first 40 minutes with Hodgson's four penalties being matched by Walder.
Four further penalties from Hodgson had looked set to hand Sale the win, despite Wasps scoring the game's only try through Dan Ward-Smith, before Walder intervened.