Some workers cannot switch off outside office hours, regularly checking texts or emails when they get home, a new study has showed.
Research revealed a third of adults feel having remote access to the office impinges on their personal life.
The Chartered Institute of Personnel and Development said its survey of 2,000 employees found two out of five regularly dealt with texts or emails outside working hours.
Almost one in five said it made them feel anxious and was even affecting their sleep.
Claire McCartney of the CIPD, said: "Flexible working has an important role to play in modern workplaces, and remote access to work can open up the jobs market to those who may not have been able to access it before.
"With the UK's decision to leave the EU causing further uncertainty around access to skills, it's more important than ever that employers make use of all the talent available to them by ensuring that their workplaces are inclusive, flexible and agile.
"However, a lack of clarity and guidance for employees around remote working can cultivate an environment where some employees feel unable to physically or mentally switch off.
"This can have adverse effects on employee well-being and their engagement with the organisation, as well as their productivity at work.
"Employers therefore need to have a clear approach to remote working as well as create a wider enabling culture, where employees feel trusted and empowered to take ownership of their work, but also able to speak out if they are struggling."