The Co Down woman at the helm of Irish economic development agency Enterprise Ireland is stepping down.
Enterprise Ireland confirmed that Julie Sinnamon is leaving the role of chief executive later this year, after six years in charge.
Its chairman Terence O'Rourke praised Ms Sinnamon's contribution to helping the growth of Irish firms around the world.
He said: "A record 221,895 people are now employed by Enterprise Ireland-backed companies, with exports of almost €24bn, the highest in the history of the agency.
"I would like to thank Julie for her work as CEO, her leadership of the Enterprise Ireland team and for her commitment and dedication in supporting our client companies, ensuring that Irish enterprise is in a very strong position for the future."
Ms Sinnamon said it had been "an honour" to lead the organisation. She added: "I will work with the organisation until later in the year to ensure an orderly transition and, in the meantime, will continue to devote all of my efforts to help colleagues and clients achieve further success in global markets."
Ms Sinnamon is a graduate of the University of Ulster. She also completed an MBA in international business at Fordham University in the US, and later an executive development programme at Stanford University.
She wrote a thesis on multinational decision-making between Northern Ireland, Scotland and the Republic of Ireland, before returning to Dublin to work for Trinity Bank.
She then joined the IDA, which was later split in two to include Enterprise Ireland.