Sir Elton John has called for a boycott of fashion brand Dolce and Gabbana after he said the designers labelled children born through IVF "synthetic".
The songwriter, who has two children with his husband David Furnish, angrily rebuked the Italian pair for criticising same-sex families and the use of fertility treatment.
Domenico Dolce and Stefano Gabbana, who are both gay and were formerly a couple, have previously voiced their rejection of same-sex marriage, but in an interview with an Italian magazine this weekend the remarks were extended to an objection to gay families.
Dolce told Panorama: "...what I call children of chemistry don't convince me, synthetic children. Wombs for hire, (are a) choice from a catalogue. And then you have to explain to this child who is the mother. To procreate ought to be an act of love, today not even psychiatrists are ready to confront the effects of these experiments."
But Sir Elton said: "How dare you refer to my beautiful children as 'synthetic'. Your archaic thinking is out of step with the times, just like your fashions. I shall never wear Dolce and Gabbana ever again."