Hugh Laurie will be back on US television in Chance, his first starring role stateside since medical drama House.
The British actor heads the cast in the psychological thriller for streaming service Hulu.
Laurie will play Eldon Chance, a San Francisco-based forensic neuropsychiatrist in the series based on Kem Nunn's novel of the same name.
Hulu has so far committed to two seasons and a total of 20 episodes.
In the series, Chance will get sucked into a violent and dangerous world of mental illness and police corruption.
He takes on a patient who may or may not be struggling with a multiple personality disorder.
Eventually, he comes to the attention of her abusive husband, who also happens to be a ruthless police detective.
Chance has a divorce and a teenage daughter to deal with, and is quickly in over his head.
In addition to starring, Laurie will also serve as executive producer.
Comparisons to House are inevitable as the 57-year-old is once again playing a maverick doctor.
As Gregory House, Laurie became an international star and an unlikely sex symbol.
The 2004-2012 series won the Brit several awards, including two Golden Globes and two Screen Actors Guilds trophies.
Misanthropic, American Doctor House was a far cry from the British buffoons that had first made Laurie a household name in the 1980s a longside comedy partner Stephen Fry.
Chance is a Fox 21 Studios production, the company behind hits including Channel 4 import Homeland and ITV Encore's The Americans.
The same company is also producing American Crime Story, the hotly anticipated OJ Simpson series starring Oscar winner Cuba Gooding Jr as Simpson.