The Queen is to base herself at Windsor Castle early and is likely to stay there beyond the Easter period as she follows the Government's latest guidance on coronavirus.
Buckingham Palace announced that the 93-year-old head of state will decamp to the Berkshire royal residence tomorrow - a week earlier than she usually does for Easter Court.
The monarch will be based at her favourite home with a reduced household and will be following appropriate advice, a source said.
Prime Minister Boris Johnson has called on all people in the UK, particularly the over-70s, to avoid all non-essential contact and travel as part of unprecedented peacetime measures aimed at trying to control the spread of Covid-19.
Elizabeth II, the nation's longest-reigning monarch, is due to celebrate her 94th birthday next month, and the risk of more severe symptoms from the coronavirus is greater for the elderly and those with pre-existing health conditions.
Buckingham Palace said public royal events with large numbers of people in the coming months would be cancelled or postponed.
Investitures will be rearranged and the annual Maundy Service at St George's Chapel has been cancelled, the palace added.