Up to 200 employees are to be furloughed by Queen's University Belfast (QUB), it has been confirmed.
Around 5% of the university's 4,000 staff will be placed on the Government-funded coronavirus scheme, including those working in commercial areas such as events, conferences, sports and catering.
QUB said furloughed staff would nevertheless continue to take home their usual monthly salary.
The university campus along with many of its facilities was closed in March due to the Covid-19 crisis.
The Coronavirus Job Retention Scheme, which has been extended until October, allows employers to temporarily lay off staff while the Government pays 80% of their wages.
In a statement the university said that some services had been reduced or temporarily suspended due to the Covid-19 outbreak and the lockdown measures in place.
"Queen's University has adapted its operations to continue to deliver education, research and key services during the pandemic in a way that protects the safety and wellbeing of staff and students," it said.
"However, some services cannot be provided in accordance with the current social distancing measures.
"The university has decided to access the Coronavirus Job Retention Scheme and temporarily furlough staff who are responsible for these services and meet the criteria of the scheme.
"This will only apply to a limited number of staff.
"The university will ensure that furloughed staff continue to receive their full salary and pension contributions as well as accrue annual leave."
Some other UK universities have said they are placing employees on the furlough scheme.
Up to 80,000 people across Northern Ireland who are shielding from Covid-19 are likely to have to continue to follow the strict lockdown measures beyond the initial 12-week recommendation, it has been warned.