Work on nearly nine miles of dual carriageway upgrading the Belfast to Londonderry road will begin this year, Transport Minister Michelle McIlveen said.
The scheme will improve the road between the end of the M22 at Randalstown and the Castledawson Roundabout and ease congestion on an arterial route. The project is expected to cost £130 million.
Ms McIlveen said: "This is a major investment for the North West and will be very welcome news for the local construction industry.
"The A6 dualling scheme is a significant project that will help to remove a major bottleneck and so improve safety and journey times on this strategically important route."
In May last year, Graham/Farrans Joint Venture was awarded the contract for the development of the A6 Randalstown to Castledawson Dualling Project.
Ms McIlveen continued: "That detailed design work is progressing and now that the Executive has confirmed funding for this section of the A6, the scheme can move ahead with work on site expected to start by the end of the summer."