The Pope's latest intervention on child abuse, days before his visit to the Irish Republic, is too little too late, a campaigner said.
Pope Francis said the church had delayed action and urged a culture of care at present and in the future as he published a strongly-worded letter on the subject.
He arrives this weekend in the Republic, where the Catholic church has been rocked by a series of sex abuse scandals involving members of religious orders.
Margaret McGuckin, leader of SAVIA (Survivors and Victims of Institutional Abuse), a charity set up to give a voice to those affected by historic abuse in Northern Ireland, said: "It is a last-ditch attempt to see what he can do.
"It is too little too late, nothing will change."
A Pennsylvania grand jury report published recently in the US found more than 300 priests abused more than 1,000 children.
The Pope expressed "shame and repentance" on behalf of the church. He added: "We acknowledge as an ecclesial community that we were not where we should have been, that we did not act in a timely manner, realising the magnitude and the gravity of the damage done to so many lives.
"We showed no care for the little ones, we abandoned them."
The Pope will meet Irish president Michael D Higgins and Taoiseach Leo Varadkar, and will address a session of the World Meeting of Families and celebrate mass at Phoenix Park.
Referring to the US abuse report, the pontiff noted that at least 1,000 survivors were victims of abuse at the hands of priests. He said: "We have realised that these wounds never disappear and that they require us forcefully to condemn these atrocities and join forces in uprooting this culture of death; these wounds never go away.
"The heart-wrenching pain of these victims, which cries out to heaven, was long ignored, kept quiet or silenced.
"But their outcry was more powerful than all the measures meant to silence it, or sought even to resolve it by decisions that increased its gravity by falling into complicity."
Ms McGuckin is urging a further public inquiry into clerical abuse in Northern Ireland.
When the Pope came to office in 2013, she thought he was a breath of fresh air. She was left disillusioned after his decision to ordain a bishop in Chile who is accused of covering up sexual abuse committed by a priest.
The Pope said: "Looking back to the past, no effort to beg pardon and to seek to repair the harm done will ever be sufficient.
"Looking ahead to the future, no effort must be spared to create a culture able to prevent such situations from happening, but also to prevent the possibility of their being covered up and perpetuated.
"The pain of the victims and their families is also our pain, and so it is urgent that we once more reaffirm our commitment to ensure the protection of minors and of vulnerable adults."
Tanaiste Simon Coveney said Pope Francis needs to offer action rather than repeat the words of his predecessors on church scandals.
Ahead of the pontiff's visit, Mr Coveney said this weekend is "a big moment for Ireland". The Tanaiste and his family will be the first people to greet Pope Francis when he touches down on Irish soil. Writing in today's Irish Independent, he said that as a practicing Catholic it would be "an honour" to welcome the Pope - but Mr Coveney added that he felt "failed" and "conflicted" by the Church. He said the way in which Pope Francis addressed "abuse victims, worshippers and a curious public in Ireland will be pivotal".
Mr Coveney noted that the Pope had been "outspoken with bluntness on big international questions such as climate change, migration and poverty".
"However the church has repeatedly failed to adequately address clerical sex abuse", he continued, adding: "Yesterday Pope Francis wrote directly to Catholics across the world begging for forgiveness and accepting the church had failed.
"The issue of clerical sex abuse was always going to feature in the Pope's visit to Ireland but the Pennsylvania report has given it new gravity."