A man and a woman have been arrested in Portugal under a European arrest warrant.
Gardai said the man, aged in his 30s, and the woman, aged in her 20s, were detained in relation to the seizure of about 187,000 euro worth of cannabis in Co Cork three years ago.
The arrests were made in Lisbon on Wednesday following a raid on a house in Dunmanway on January 18 2016.
Officers from the West Cork drugs unit discovered cannabis herb and cannabis plants at the property.
Previously, four men and a woman had been arrested and detained at Bandon and Bantry garda stations in relation to the case but they were later released without charge.
A file was prepared for the DPP.
The man and the woman detained in Portugal were brought back to Ireland to face charges.
They are being detained at Bandon garda station and were due to appear before Bantry district court on Thursday afternoon.
One man has already been before the courts in relation to the matter.
Another European arrest warrant remains outstanding.