Twelve people were injured when a bus crashed into a tree in east London.
A man is his forties is being treated for a head injury, and a woman in her sixties suffered hip pain after the collision near Manor Park station in Newham.
Another eight people were taken to hospitals in the city for treatment.
Photographs of the single decker red bus, carrying 15 passengers, showed it resting on a grassy verge having hit the tree on its far side.
Police said that no arrests had been made and their inquiries are continuing.
A spokeswoman for London Ambulance Service said: "We were called at 11:59am to reports of a road traffic collision involving a bus and a tree at Manor Park station.
"We sent a number of resources to the scene including six ambulances, four duty officers, our hazardous area response team, London's Air Ambulance and our emergency planning team."
London Fire Brigade also attended the accident.
In a separate incident in the West Midlands, two bus drivers had to be cut free from their cabs after a collision between a single decker and double decker bus.
Six passengers were taken to hospital following the crash on Addison Road, in south Birmingham this morning.
A spokesman for West Midlands Ambulance Service said both drivers were treated for leg injuries once they were freed and taken to Queen Elizabeth Hospital Birmingham.
He said: "Both men appear to have escaped serious injuries which given the significance of the collision is extremely fortunate.
"One of the passengers on the single decker bus, an elderly female, had to be helped from the vehicle on a stretcher. She was treated for back injuries and taken to the same hospital."
Ten other patients were assessed and treated at the scene by the Hazardous Area Response Team (HART), three of which were sent to Queen Elizabeth Hospital Birmingham by ambulance.
The remaining seven passengers were discharged at the scene.