The organisers of tonight's Children In Need appeal are hoping to beat last year's record-breaking total with the help of stars including One Direction, Sir Bruce Forsyth and the EastEnders cast.
Veteran host Sir Terry Wogan is sharing presenting duties with Tess Daly, Fearne Cotton, Nick Grimshaw and Rochelle Humes from 7.30pm with the show running until 2am.
Among the acts performing on the night are the newly reunited S Club 7, Cheryl Fernandez-Versini and Susan Boyle.
Last year's show ended with Sir Terry unveiling a record-breaking total of £31 million.
He said: "It was my privilege to present the very first Children In Need in 1980 and over the years it has truly become the British public's charity.
"Their extraordinary generosity has meant that their donations of over £740 million have made a real difference to the lives of this country's disadvantaged children and young people.
"It's an honour and pleasure to be part of a great charity and I am looking forward to presenting an evening full of entertainment with the usual suspects, Tess, Fearne, Nick and our new host Rochelle."
There will also be an appearance from Tom and Jerry who are starring in a new cartoon specially made for Children In Need.
One Direction are performing live in Albert Square and one of Walford's longest-serving residents, Ian Beale, will have a haunting reunion with some of the women in his life.
Gareth Malone and his All-Star Choir, starring amongst others Jo Brand, Mel Giedroyc and Craig Revel-Horwood, will perform the charity's official single and there will be a special episode of Strictly Come Dancing.