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First cases of worrying Manaus variant of Covid-19 found in UK

The first two cases of the P.1 strain are from one household in South Gloucestershire with a history of travel to Brazil but the third is not linked.

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A coronavirus test is handed out of a car window (Andrew Matthews/PA)

A coronavirus test is handed out of a car window (Andrew Matthews/PA)

A coronavirus test is handed out of a car window (Andrew Matthews/PA)

Officials have identified the first UK cases of the Manaus variant of coronavirus, a new strain that may spread more rapidly and respond less well to existing vaccines.

Public Health England (PHE) said on Sunday that six cases of the concerning P.1 variant first detected in the Brazilian city have been confirmed in Britain, three in England and three in Scotland.

Two were confirmed in South Gloucestershire but the third English case has not been located and could be anywhere in the nation, as PHE says the person did not complete their test registration card so their contact details are unavailable.

Anyone who took a test on February 12 or 13 and has not received a result, or has an uncompleted test registration card, is being asked to come forward immediately.

Critics said the development exposed the “weaknesses” in the border protections against new strains and condemned the Government for delaying toughening restrictions.

The Gloucestershire cluster was said to originate from one individual who travelled back from Brazil and arrived in London on February 10 – five days before the Government’s quarantine hotel policy came into force.

So, the traveller isolated at home with the rest of their household. One member was understood to have developed symptoms before getting a test.

It is understood there were four positive tests in total in that household, two of which were confirmed with genetic sequencing to be the P.1 variant.

But officials are awaiting the results of sequencing on the outstanding two tests to see if they were infected by the Manaus strain.

This troubling development shows the weaknesses in the Government’s Covid border measuresYvette Cooper

PHE and NHS Test and Trace are contacting the passengers on Swiss Air flight LX318 travelling from Sao Paulo, through Zurich, and landing in London Heathrow on February 10.

Surge testing will be carried out in the Bradley Stoke, Patchway and Little Stoke areas of South Gloucestershire.

The remaining unlocated case is not believed to be linked to the others because the virus was found to have slight genetic differences.

Officials said their test was processed on February 14, so believe it is likely they took it a day or two earlier.

They believe that person is unlikely to have taken their test at one of the regional test sites, where staff can check if contact details have been provided, but it could have been a home test or from local surge testing.

The Scottish Government said three residents who returned to north-east Scotland from Brazil, via Paris and London, subsequently tested positive for Covid-19.

The tests, completed in early February, were passed to the UK’s sequencing programme and were identified as being the Manaus variant.

Officials are contacting the other passengers on their flight from London to Aberdeen.

The cases are not thought to be connected to the three confirmed cases in England.

The World Health Organisation has been informed of the cases, which have been designated “of concern” as it shares key mutations with the variant detected in South Africa.

More work is needed but there are concerns that the existing vaccines may be less effective against the Manaus strain.

NHS England national medical director Professor Stephen Powis sought to allay concerns by saying vaccines can be quickly altered to tackle new strains.

“The new vaccines which are being used for Covid can be adapted very rapidly so it’s likely that if we do need to change the vaccine that can be done in months, rather than years, which was the case with the more traditional vaccines,” he told BBC News.

It is understood that officials became aware of the English cases on Friday and the Scottish ones on Saturday.

The chairwoman of the Commons Home Affairs Committee, Labour MP Yvette Cooper, said: “This troubling development shows the weaknesses in the Government’s Covid border measures.

“The Brazil variant was first identified a month before one of these cases was brought in on February 10 and many weeks after the Prime Minister was warned that indirect flights were a problem, yet the Government delayed putting stronger measures in place.

“We need to know urgently how all these cases have arrived in the country and why they weren’t prevented or picked up on arrival so that lessons can be quickly learnt and policies changed to protect the vaccine programme from further cases arriving.”

Shadow home secretary Nick Thomas-Symonds said the detection of the variant in the UK was “deeply concerning”.

“It is now vital that we do everything we can to contain it,” the Labour MP said.

“But this is further proof that the delay in introducing a hotel quarantine was reckless and the continuing refusal to put in place a comprehensive system leaves us exposed to mutations coming from overseas.”

This new variant demonstrates how serious Covid is and reinforces the need to minimise the spread of the virusJeane Freeman

The quarantine hotel policy to protect the UK against new variants came into force on February 15 after much delay.

It means those returning from “red list” countries, including Brazil, must quarantine in Government-designated hotels for 10 days at a cost of £1,750 for a single adult.

Chancellor Rishi Sunak said during a BBC interview on Sunday morning he had not received any evidence of new variants having emerged when questioned about concerns that case rates are rising in one in five areas.

Scottish Health Secretary Jeane Freeman said: “The identification of this new variant is a concern but we are taking every possible precaution.

“This new variant demonstrates how serious Covid is and reinforces the need to minimise the spread of the virus.”

The disclosure of the variant’s presence came shortly after the Government said that 20 million people in the UK have now been given their first dose of a vaccine.

Prime Minister Boris Johnson said it was a “huge national achievement”, after a rise of 407,503 first jabs in a day.

Meanwhile, a further 144 people had died within 28 days of testing positive for Covid-19 as of Sunday, bringing the official UK death toll to 122,849.

PA


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