A participant of a breakthrough drug trial in treating Covid-19 has said he would not be here today if he had not been involved.
John Hanna, from Inverclyde, was so ill with the virus in 2020, he was placed in a medically induced coma.
His wife enrolled him in the Recovery trial for dexmethasone, which is now estimated to have saved one million lives around the world – including 22,000 in the UK.
That decision changed everything. Without the doctors and research teams working around the clock to find out which treatments worked, and which didn’t, I wouldn’t be here todayJohn Hanna
He said: “My wife enrolled me in the Recovery trial as a last ray of hope for treatment.
“That decision changed everything. Without the doctors and research teams working around the clock to find out which treatments worked, and which didn’t, I wouldn’t be here today.”
On June 16 2020, researchers found dexamethasone reduced deaths by up to one third in what was a breakthrough for the study which was announced on the first day of the national UK lockdown on March 23, 2020.
It was primarily funded by UK Research and Innovation (UKRI), and the National Institute for Health and Care Research (NIHR) with a joint investment of £2.1 million, after a call for research proposals in early February 2020.
After two weeks, 1,000 participants had joined the trial and five weeks later, 10,000 people had joined.
The study also found that antimalarial drug hydroxychloroquine had no clinical benefit and lopinavir-ritonavir was not effective in reducing deaths.
Prof Patrick Chinnery, clinical director at UKRI’s Medical Research Council said: “Many patient lives have been saved by using dexamethasone in patients with severe Covid-19.
“Two years on, we reflect on the incredible efforts from all those involved in the trials which helped us tackle the pandemic.”