A 40-year-old inmate has been found hanged in his cell, the Prison Service said.
Paul O'Connor was found hanging in his cell at HMP Birmingham shortly before 2.30pm on Saturday.
Staff at the prison attempted to resuscitate him before an ambulance took him to City Hospital. He was pronounced dead at about 2am.
A Prison Service spokesman said: "As with all deaths in custody, the Prisons and Probation Ombudsman will conduct an investigation."